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Genetics

Cr/Prl, One silver copy

Cr/Prl

The two recorded alleles act together.

Incomplete dominant

One cream copy · Cr/Prl About Cream

Recorded as showing this trait.

How do you know?

DNA test reported by owner

Original wording: "Cr/Prl".

One pearl copy · Cr/Prl About Pearl

One copy is recorded. This trait can be passed on without showing.

How do you know?

DNA test reported by owner

One silver copy · Z/N About Silver

Recorded as showing this trait.

Dominant

How do you know?

DNA test reported by owner

Reported risk: Multiple congenital ocular anomalies have been reported with one or two silver copies, including in chestnut horses. One-copy horses generally have milder findings; two-copy horses tend to have more severe abnormalities that can affect vision.

Andersson LS, Wilbe M, Viluma A, Cothran G, Ekesten B, Ewart S, Lindgren G (2013) PLoS ONE 8:e75639, Equine Multiple Congenital Ocular Anomalies and Silver Coat Colour Result from the Pleiotropic Effects of Mutant PMELKomaromy AM, Rowlan JS, La Croix NC, Mangan BG (2011) Vet Ophthalmol, Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies: five casesUC Davis Veterinary Genetics Laboratory, Multiple Congenital Ocular Anomalies (MCOA) (VGL test page)Andersson LS, Wilbe M, Viluma A, Cothran G, Ekesten B, Ewart S, Lindgren G (2013) PLoS ONE 8:e75639, Equine Multiple Congenital Ocular Anomalies and Silver Coat Colour Result from the Pleiotropic Effects of Mutant PMELKomaromy AM, Rowlan JS, La Croix NC, Mangan BG (2011) Vet Ophthalmol, Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies: five casesUC Davis Veterinary Genetics Laboratory, Multiple Congenital Ocular Anomalies (MCOA) (VGL test page)Andersson LS, Wilbe M, Viluma A, Cothran G, Ekesten B, Ewart S, Lindgren G (2013) PLoS ONE 8:e75639, Equine Multiple Congenital Ocular Anomalies and Silver Coat Colour Result from the Pleiotropic Effects of Mutant PMELKomaromy AM, Rowlan JS, La Croix NC, Mangan BG (2011) Vet Ophthalmol, Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies: five casesUC Davis Veterinary Genetics Laboratory, Multiple Congenital Ocular Anomalies (MCOA) (VGL test page)