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Genetics

Gray (zygosity unknown), Gray G2 (not confirmed), Gray G3 (not confirmed)

Gray (zygosity unknown) · G_ About Gray

Recorded as showing this trait. One or two copies are not known.

Dominant

How do you know?

DNA test reported by owner

Test scope: Gray, Gray G2, Gray G3

Original wording: "Unresolvable, four STX17 copies detected".

Reported risk: Population studies report dermal melanomas in about two thirds to three quarters of gray horses over 15, often under the tail and around the head.

Fleury C, Berard F, Leblond A, Faure C, Ganem N, Thomas L (2000) Pigment Cell Res 13:47-51, The study of cutaneous melanomas in Camargue-type gray-skinned horses (2): epidemiological surveySeltenhammer MH, Simhofer H, Scherzer S, Zechner R, Curik I, Solkner J, et al. (2003) Equine Vet J 35:153-157, Equine melanoma in a population of 296 grey Lipizzaner horsesRosengren Pielberg G, Golovko A, Sundstrom E, ... Solkner J, Andersson L (2008) Nat Genet 40:1004-1009, A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse

Reported risk: Gray horses have been reported to be overrepresented among cases of ocular squamous cell carcinoma. This is a coat-color association; a causal effect of the gray allele has not been established.

Crausaz M, Launois T, Smith-Fleming K, McCoy AM, Knickelbein KE, Bellone RR 2020, Genes (Basel), DDB2 Genetic Risk Factor for Ocular Squamous Cell Carcinoma Identified in Three Additional Horse BreedsDugan SJ, Curtis CR, Roberts SM, Severin GA 1991, J Am Vet Med Assoc 198:251-256, Epidemiologic study of ocular/adnexal squamous cell carcinoma in horsesUC Davis Veterinary Genetics Laboratory, Gray Copy Number (VGL test page)
Gray G2 · not confirmed

This trait has not been confirmed.

Dominant

How do you know?

DNA test reported by owner

Test scope: Gray, Gray G2, Gray G3

Gray G3 · not confirmed

This trait has not been confirmed.

Dominant

How do you know?

DNA test reported by owner

Test scope: Gray, Gray G2, Gray G3