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Genetics

One cream copy, E/e, Gray (zygosity unknown), Pearl (tested clear (Cream (Cr), Pearl (Prl)))

One cream copy · Cr/N About Cream

Recorded as showing this trait.

Incomplete dominant

How do you know?

DNA test reported by owner

Test scope: Cream (Cr), Pearl (Prl)

Original wording: "N/Cr".

E/e

The two recorded alleles act together.

Dominant

One E copy · E/e

Recorded as showing this trait.

How do you know?

DNA test reported by owner

Original wording: "E/e".

One red factor copy · E/e About Red Factor

One copy is recorded. This trait can be passed on without showing.

How do you know?

DNA test reported by owner

Gray (zygosity unknown) · G_ About Gray

Recorded as showing this trait. One or two copies are not known.

Dominant

How do you know?

DNA test reported by owner

Original wording: "Gray: detected".

Reported risk: Population studies report dermal melanomas in about two thirds to three quarters of gray horses over 15, often under the tail and around the head.

Fleury C, Berard F, Leblond A, Faure C, Ganem N, Thomas L (2000) Pigment Cell Res 13:47-51, The study of cutaneous melanomas in Camargue-type gray-skinned horses (2): epidemiological surveySeltenhammer MH, Simhofer H, Scherzer S, Zechner R, Curik I, Solkner J, et al. (2003) Equine Vet J 35:153-157, Equine melanoma in a population of 296 grey Lipizzaner horsesRosengren Pielberg G, Golovko A, Sundstrom E, ... Solkner J, Andersson L (2008) Nat Genet 40:1004-1009, A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse

Reported risk: Gray horses have been reported to be overrepresented among cases of ocular squamous cell carcinoma. This is a coat-color association; a causal effect of the gray allele has not been established.

Crausaz M, Launois T, Smith-Fleming K, McCoy AM, Knickelbein KE, Bellone RR 2020, Genes (Basel), DDB2 Genetic Risk Factor for Ocular Squamous Cell Carcinoma Identified in Three Additional Horse BreedsDugan SJ, Curtis CR, Roberts SM, Severin GA 1991, J Am Vet Med Assoc 198:251-256, Epidemiologic study of ocular/adnexal squamous cell carcinoma in horsesUC Davis Veterinary Genetics Laboratory, Gray Copy Number (VGL test page)
Pearl · tested clear (Cream (Cr), Pearl (Prl)) About Pearl

Recorded as absent within the stated test scope.

Recessive

How do you know?

DNA test reported by owner

Test scope: Cream (Cr), Pearl (Prl)

How the owner describes it

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